ML385
Cat. No.：YN410001
CAS No. ：846557-71-9
| 产品名称: | ML385 |
| CAS No.: | 846557-71-9 |
| Chemical Name: | N-[4-[2,3-dihydro-1-(2-methylbenzoyl)-1H-indol-5-yl]-5-methyl-2-thiazolyl]-1,3-benzodioxole-5-acetamide |
| Synonyms: | ML 385; ML-385 |
| 分子量: | 511.59 |
| 分子式: | C₂₉H₂₅N₃O₄S |
| SMILES: | O=C(NC1=NC(C2=CC=C(N(C(C3=C(C)C=CC=C3)=O)CC4)C4=C2)=C(C)S1)CC5=CC(OCO6)=C6C=C5 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | ML385是特异的NRF2抑制剂，IC50为1.9 μM。 |
| IC50和靶点: | |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
Singh, A., Venkannagari, S., Oh, K.H., et al.Small molecule inhibitor of NRF2 selectively intervenes therapeutic resistance in KEAP1-deficient NSCLC tumorsACS Chem Biol.11(11),3214-3225(2016)
