Hesperin
Cat. No.：YN410005
| 产品名称: | Hesperin |
| CAS No.: | 4430-35-7 |
| Chemical Name: | 1-isothiocyanato-6-(methylsulfinyl)-hexane |
| Synonyms: | 6-Methylsulfinylhexyl Isothiocyanate;1-ISOTHIOCYANATO-6-(METHYLSULFINYL)-HEXANE;1-isothiocyanato-6-methylsulfinylhexane;6-Methylsulfinylhexy;(6-Isothiocyanato-hexyl)-methyl-sulfoxid;6-(methylsulfinyl)hexyl isothiocyanate;CHEMBL573428;CTK1D2491;Hexane, 1-i |
| 分子量: | 205.34 |
| 分子式: | C₈H₁₅NOS₂ |
| SMILES: | O=S(CCCCCCN=C=S)C |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Hesperin 是日本芥末中存在的一种生物活性成分，是一种Nrf2活化剂。 |
| IC50和靶点: | |
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Noshita, T., Kidachi, Y., Funayama, H., et al.Anti-nitric oxide production activity of isothiocyanates correlates with their polar surface area rather than their lipophilicityEur. J. Med. Chem.44(12),4931-4936(2009)
Morimitsu, Y., Hayashi, K., Nakagawa, Y., et al.Antiplatelet and anticancer isothiocyanates in Japanese domestic horseradish, WasabiMech. Ageing Dev.116(2-3),125-134(2000)
Nomura, T., Shinoda, S., Yamori, T., et al.Selective sensitivity to wasabi-derived 6-(methylsulfinyl)hexyl isothiocyanate of human breast cancer and melanoma cell lines studied in vitroCancer Detect. Prev.29(2),155-160(2005)
Morroni, F., Sita, G., Tarozzi, A., et al.Neuroprotection by 6-(methylsulfinyl)hexyl isothiocyanate in a 6-hydroxydopamine mouse model of Parkinson's diseaseBrain Res.1589,93-104(2014)
Fuke, Y., Shinoda, S., Nagata, I., et al.Preventive effect of oral administration of 6-(methylsulfinyl)hexyl isothiocyanate derived from wasabi (Wasabia japonica Matsum) against pulmonary metastasis of B16-BL6 mouse melanoma cellsCancer Detect. Prev.30(2),174-179(2006)
