CDDO-dhTFEA
Cat. No.：YN410019
CAS No. ：1191265-33-4
| 产品名称: | CDDO-dhTFEA |
| CAS No.: | 1191265-33-4 |
| Chemical Name: | |
| Synonyms: | RTA dh404 |
| 分子量: | 574.72 |
| 分子式: | C₃₃H₄₅F₃N₂O₃ |
| SMILES: | CC(C)([C@](CC[C@@]([C@@]1(CC[C@]2(CCC(C)(C[C@]2([C@]13[H])[H])C)C(NCC(F)(F)F)=O)C)4C)5[H])C(C(C#N)=C[C@]5(C)[C@@]4([H])CC3=O)=O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | CDDO-dhTFEA (RTA dh404) 是一种合成的齐墩果烷三萜化合物，有效激活Nrf2并抑制促炎转录因子NF-κB。 CDDO-dhTFEA 可以恢复高血压 (MAP)，增加 Nrf2 及其靶基因的表达，减弱 NF-κB 的活化和转化生长因子-β 途径，并减少慢性肾病 (CKD) 大鼠的肾小球硬化，间质纤维化和炎症。 |
| IC50和靶点: | |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
