4-Octyl Itaconate
Cat. No.：YN410020
CAS No. ：3133-16-2
| 产品名称: | 4-Octyl Itaconate |
| CAS No.: | 3133-16-2 |
| Chemical Name: | 2-methylene-butanedioic acid, 4-octyl ester |
| Synonyms: | 4-辛基衣康酸,衣康酸盐 |
| 分子量: | 242.31 |
| 分子式: | C₁₃H₂₂O₄ |
| SMILES: | O=C(OCCCCCCCC)CC(C(O)=O)=C |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | 4-Octyl Itaconate 是一种可透过细胞的 Itaconate 衍生物。Itaconate 是一种抗炎代谢产物，通过 KEAP1 的烷基化而活化Nrf2。 |
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Michelucci, A., Cordes, T., Ghelfi, J., et al.Immune-responsive gene 1 protein links metabolism to immunity by catalyzing itaconic acid productionProc. Natl. Acad. Sci. USA110(19),7820-7825(2013)
Mills, E.L., Ryan, D.G., Prag, H.A., et al.Itaconate is an anti-inflammatory metabolite that activates Nrf2 via alkylation of KEAP1Nature556(7699),113-117(2018)
