Keap1-Nrf2-IN-1
Cat. No.:YN410033
CAS No. :2232112-72-8
产品名称: | Keap1-Nrf2-IN-1 |
CAS No.: | 2232112-72-8 |
Chemical Name: | |
Synonyms: | Keap1–Nrf2-IN-1 |
分子量: | 484.52 |
分子式: | C₂₄H₂₄N₂O₇S |
SMILES: | OC([C@H]1N(C2=CC=C(N(CC(O)=O)S(C3=CC=C(OC)C=C3)(=O)=O)C4=C2C=CC=C4)CCC1)=O |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | Keap1-Nrf2-IN-1 (compound35) 是一种Keap1-Nrf2蛋白-蛋白相互作用抑制剂,对 Keap1 蛋白作用的IC50值为 43 nM。Keap1-Nrf2-IN-1 能激活 Nrf2 调节的细胞保护反应,并在细胞和体内模型中对乙酰氨基酚诱导的肝损伤产生拮抗作用。 |
IC50和靶点: | |
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In Vivo: | |
Clinical Trial: | |
Solvent & Solubility: |