Astilbin
Cat. No.：YN410106
CAS No. ：29838-67-3
| 产品名称: | Astilbin |
| CAS No.: | 29838-67-3 |
| Chemical Name: | (2R,3R)-3-[(6-deoxy-α-L-mannopyranosyl)oxy]-2-(3,4-dihydroxyphenyl)-2,3-dihydro-5,7-dihydroxy-4H-1-benzopyran-4-one |
| Synonyms: | 落新妇苷 |
| 分子量: | 450.39 |
| 分子式: | C₂₁H₂₂O₁₁ |
| SMILES: | O=C1[C@@H]([C@@H](C2=CC(O)=C(O)C=C2)OC3=CC(O)=CC(O)=C13)O[C@@](O[C@@H](C)[C@H](O)[C@H]4O)([H])[C@@H]4O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Astilbin 是一种黄酮类化合物，可从Smilax glabra根茎中分离。Astilbin 增强NRF2活化。Astilbin 还抑制TNF-α表达和NF-κB活化。 |
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Wang, S.-w., Xu, Y., Weng, Y.-y., et al.Astilbin ameliorates cisplatin-induced nephrotoxicity through reducing oxidative stress and inflammationFood Chem. Toxicol.114,227-236(2018)
Zhu, Y.-L., Sun, M.-F., Jia, X.-B., et al.Neuroprotective effects of Astilbin on MPTP-induced Parkinson's disease mice: Glial reaction, α-synuclein expression and oxidative stressInt. Immunopharmacol.66,19-27(2019)
Sun, X., Zhang, H., Zhang, Y., et al.Caspase-dependent mitochondrial apoptotic pathway is involved in astilbin-mediated cytotoxicity in breast carcinoma cellsOncol. Rep.40(4),2278-2286(2018)
