D-AP5
Cat. No.：YN360044
CAS No. ：79055-68-8
| 产品名称: | D-AP5 |
| CAS No.: | 79055-68-8 |
| Chemical Name: | 5-phosphono-D-norvaline |
| Synonyms: | D-APV; D-2-Amino-5-phosphonovaleric acid |
| 分子量: | 197.13 |
| 分子式: | C₅H₁₂NO₅P |
| SMILES: | N[C@H](CCCP(O)(O)=O)C(O)=O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | D-AP5 (D-APV) 是一种选择性和竞争性NMDA受体拮抗剂，Kd为 1.4 μM。D-AP5 抑制 NMDA 受体的谷氨酸结合位点。 |
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Evans, R.H., Francis, A.A., Jones, A.W., et al.The effects of a series of ω-phosphonic α-carboxylic amino acids on electrically evoked and excitant amino acid-induced responses in isolated spinal cord preparationsBr. J. Pharmacol.75(1),65-75(1982)
Morris, R.J.Synaptic plasticity and learning: Selective impairment of learning rats and blockade of long-term potentiation in vivo by the N-methyl-D-aspartate receptor antagonist AP5J. Neurosci.9(9),3040-3057(1989)
