7-Chlorokynurenic acid sodium salt
Cat. No.:YN360057
CAS No. :1263094-00-3
产品名称: | 7-Chlorokynurenic acid sodium salt |
CAS No.: | 1263094-00-3 |
Chemical Name: | |
Synonyms: | 7-CKA sodium salt |
分子量: | 245.59 |
分子式: | C₁₀H₅ClNNaO₃ |
SMILES: | O=C(C1=NC2=CC(Cl)=CC=C2C(O)=C1)O[Na] |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | 7-Chlorokynurenic acid sodium salt (7-CKA sodium salt) 是一种有效且选择性的 N-methyl-D-aspartate (NMDA) 受体的甘氨酸 B 激动剂位点拮抗剂 (IC50=0.56 μM)。7-Chlorokynurenic acid sodium salt 也是谷氨酸重摄取到突触小泡中的有效抑制剂,Ki为 0.59 μM。7-Chlorokynurenic acid sodium salt 在神经传递后具有有效的镇痛作用。 |
IC50和靶点: | |
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Clinical Trial: | |
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