ATPA
Cat. No.:YN360073
产品名称: | ATPA |
CAS No.: | 140158-50-5 |
Chemical Name: | α-Amino-5-(1,1-dimethylethyl)-2,3-dihydro-3-oxo-4-isoxazolepropanoic Acid; |
Synonyms: | |
分子量: | 228.25 |
分子式: | C₁₀H₁₆N₂O₄ |
SMILES: | O=C(O)C(N)CC1=C(C(C)(C)C)ONC1=O |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | ATPA 是一种选择性的谷氨酸受体GluR5激活剂,对 GluR5wt,GluR5(S741M),GluR5(S721T),GluR5(S721T, S741M),GluR5(S741A),GluR5(S741L) 和 GluR5(S741V) 的EC50分别为 0.66,9.5,1.4,23,32,18 和 14 μM。 |
IC50和靶点: | |
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In Vivo: | |
Clinical Trial: | |
Solvent & Solubility: |
(1) Procter, M. J., et al.: Neuropharmacology 37, 1287 (1998) & (2) Frydenvang, K., et al. Structural Chemistry 13, 479 (2002) & (3) Lv, Q., et al.: Brain Res 1456, 1 (2012)