SYM 2081
Cat. No.:YN360074
CAS No. :31137-74-3
产品名称: | SYM 2081 |
CAS No.: | 31137-74-3 |
Chemical Name: | (4R)-4-Methyl-L-glutamic Acid; SYM-2081; erythro-L-4-Methylglutamic Acid; L-erythro-γ-Methylglutamic Acid; |
Synonyms: | |
分子量: | 161.16 |
分子式: | C₆H₁₁NO₄ |
SMILES: | N[C@@H](C[C@@H](C)C(O)=O)C(O)=O |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | SYM 2081 是一种有效,高选择性的红藻氨酸受体 (kainate receptor)激动剂,抑制 [3H]-kainate 的结合,IC50为 35 nM, 选择性分别是 AMPA 和 NMDA 的 3000 倍和 200 倍。 |
IC50和靶点: | |
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In Vivo: | |
Clinical Trial: | |
Solvent & Solubility: |
Jones, K.A., et al.: Neuropharmacology, 36, 853 (1997), Shou, L.M., et al.: J. Pharmacol. Exper. Therap., 280, 422 (1997),Toms, N.J., et al.: Neuropharmacology, 36, 1483 (1997), Ta, L.E., et al.: Brain Res., 858, 106 (2000),