CIQ
Cat. No.：YN360658
| 产品名称: | CIQ |
| CAS No.: | 486427-17-2 |
| Chemical Name: | (3-chlorophenyl)[3,4-dihydro-6,7-dimethoxy-1-[(4-methoxyphenoxy)methyl]-2(1H)-isoquinolinyl]-methanone |
| Synonyms: | (3-Chlorophenyl){6,7-dimethoxy-1-[(4-methoxyphenoxy)methyl]-3,4-d ihydro-2(1H)-isoquinolinyl}methanone;CIQ;(3-Chlorophenyl)[3,4-dihydro-6,7-dimethoxy-1-[(4-methoxyphenoxy)methyl]-2(1H)-isoquinolinyl]-methanone |
| 分子量: | 467.94 |
| 分子式: | C₂₆H₂₆ClNO₅ |
| SMILES: | O=C(C1=CC=CC(Cl)=C1)N2C(COC3=CC=C(OC)C=C3)C4=C(C=C(OC)C(OC)=C4)CC2 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | CIQ是一种亚基选择性的NMDA受体增强剂, 作用于NR2C或NR2D亚基。 |
| IC50和靶点: | |
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Mullasseril, P., Hansen, K.B., Vance, K.M., et al.A subunit-selective potentiator of NR2C- and NR2D-containing NMDA receptorsNat. Commun.1:90,(2010)
Monaghan, D.T., Irvine, M.W., Costa, B.M., et al.Pharmacological modulation of NMDA receptor activity and the advent of negative and positive allosteric modulatorsNeurochem Int.61(4),581-592(2012)
Hackos, D.H., and Hanson, J.E.Diverse modes of NMDA receptor positive allosteric modulation: Mechanisms and consequencesNeuropharmacology112(Pt A),34-45(2017)
