Traxoprodil
Cat. No.：YN361097
CAS No. ：134234-12-1
| 产品名称: | Traxoprodil |
| CAS No.: | 134234-12-1 |
| Chemical Name: | 4-hydroxy-αS-(4-hydroxyphenyl)-βS-methyl-4-phenyl-1-piperidineethanol |
| Synonyms: | 曲索罗地,CP101606 |
| 分子量: | 327.42 |
| 分子式: | C₂₀H₂₅NO₃ |
| SMILES: | OC1(C2=CC=CC=C2)CCN([C@@H](C)[C@@H](O)C3=CC=C(O)C=C3)CC1 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Traxoprodil (CP101,606) 是一种有效的和选择性的NMDA拮抗剂，保护海马神经元的IC50值为10 nM。 |
| IC50和靶点: | |
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| Solvent & Solubility: |
Chazot, P.L., Lawrence, S., and Thompson, C.L.Studies on the subtype selectivity of CP-101,606: Evidence for two classes of NR2B-selective NMDA receptor antagonistsNeuropharmacology42(3),319-324(2002)
Taniguchi, K., Shinjo, K., Mizutani, M., et al.Antinociceptive activity of CP-101,606, an NMDA receptor NR2B subunit antagonistBr. J. Pharmacol.122(5),809-812(1997)
Steece-Collier, K., Chambers, L.K., Jaw-Tsai, S.S., et al.Antiparkinsonian actions of CP-101,606, an antagonist of NR2B subunit-containing N-methyl-d-aspartate receptorsExp. Neurol.163(1),239-243(2000)
