Arginase inhibitor 1
Cat. No.:YN330323
CAS No. :1345808-25-4
产品名称: | Arginase inhibitor 1 |
CAS No.: | 1345808-25-4 |
Chemical Name: | (αR)-α-amino-α-(4-boronobutyl)-1-piperidinebutanoic acid |
Synonyms: | |
分子量: | 286.18 |
分子式: | C₁₃H₂₇BN₂O₄ |
SMILES: | O=C(O)[C@@](CCN1CCCCC1)(N)CCCCB(O)O |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | Arginase inhibitor 1 是一种有效的人精氨酸酶 (arginases I和II)抑制剂,IC50分别为 223 和 509 nM。 |
IC50和靶点: | |
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In Vivo: | |
Clinical Trial: | |
Solvent & Solubility: |
Van Zandt, M.C., Whitehouse, D.L., Golebiowski, A., et al.Discovery of (R)-2-amino-6-borono-2-(2-(piperidin-1-yl)ethyl)hexanoic acid and congeners as highly potent inhibitors of human arginases I and II for treatment of myocardial reperfusion injuryJ. Med. Chem.56(6),2568-2580(2013)