CK1-IN-1
Cat. No.:YN450039
产品名称: | CK1-IN-1 |
CAS No.: | 1784751-20-7 |
Chemical Name: | 4-[2-(1-fluoro-2-naphthalenyl)-4-(4-fluorophenyl)-1H-imidazol-5-yl]-pyridine |
Synonyms: | PUN51207 |
分子量: | 383.39 |
分子式: | C₂₄H₁₅F₂N₃ |
SMILES: | FC1=CC=C(C2=C(C3=CC=NC=C3)NC(C4=CC=C5C=CC=CC5=C4F)=N2)C=C1 |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | CK1-IN-1 是一种酪蛋白激酶 1(CK1)抑制剂,对 CK1δ、CK1ε、p38σ MAPK 的IC50值为 15 nM, 16 nM, 73 nM,详细信息请参考专利 WO2015119579A1,化合物 1c。 |
IC50和靶点: | [{name:"CKIδ:15 nM (IC50)"}] |
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Clinical Trial: | |
Solvent & Solubility: |
Zhong, Q., Laco, F., Liao, M.-C., et al.Influencing the fate of cardiac and neural stem cell differentiation using small molecule inhibitors of ALK5Stem Cells Transl. Med.7(10),709-720(2018)