MRT00033659
Cat. No.:YN450046
产品名称: | MRT00033659 |
CAS No.: | 1401731-54-1 |
Chemical Name: | |
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分子量: | 266.30 |
分子式: | C₁₅H₁₄N₄O |
SMILES: | CC1=NNC2=NC=C(C=C21)C3=CC=CC(NC(C)=O)=C3 |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | MRT00033659 是一种有效的广谱激酶抑制剂,抑制CK1(对 CK1δ:IC50=0.9 µM) 和CHK1(IC50=0.23 µM)。MRT00033659 是一种吡唑并吡啶类似物,可以诱导p53途径活化和 E2F-1 不稳定。 |
IC50和靶点: | [{name:"CKIδ:0.9 μM (IC50)"},{name: "Chk1:0.23 μM (IC50)"}] |
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Clinical Trial: | |
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