Oxotremorine M iodide
Cat. No.：YN320138
CAS No. ：3854-04-4
| 产品名称: | Oxotremorine M iodide |
| CAS No.: | 3854-04-4 |
| Chemical Name: | N,N,N-trimethyl-4-(2-oxo-1-pyrrolidinyl)-2-butyn-1-aminium, monoiodide |
| Synonyms: | 碘化氧化震颤素M,Oxotremorine methiodide |
| 分子量: | 322.19 |
| 分子式: | C₁₁H₁₉IN₂O |
| SMILES: | O=C1N(CC#CC[N+](C)(C)C)CCC1.[I-] |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Oxotremorine M iodide 是一种有效的，非选择性毒蕈碱型乙酰胆碱受体 (mAChR) 激动剂。Oxotremorine M iodide 通过毒蕈碱受体依赖和独立机制增强 NMDA 受体。 |
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Tran, J.A., Matsui, M., and Ehlert, F.J.Differential coupling of muscarinic M1, M2, and M3 receptors to phosphoinositide hydrolysis in urinary bladder and longitudinal muscle of the ileum of the mouseJ. Pharmacol. Exp. Ther.318(2),649-656(2006)
Caulfield, M.P., and Brown, D.A.Pharmacology of the putative M4 muscarinic receptor mediating Ca-current inhibition in neuroblastoma x glioma hybrid (NG 108-15) cellsBr. J. Pharmacol.104(1),39-44(1991)
Zwart, R., Reed, H., Clarke, S., et al.A novel muscarinic receptor-independent mechanism of KCNQ2/3 potassium channel blockade by Oxotremorine-MEur. J. Pharmacol.791,221-228(2016)
