Zamifenacin fumarate
Cat. No.：YN320332
CAS No. ：127308-98-9
| 产品名称: | Zamifenacin fumarate |
| CAS No.: | 127308-98-9 |
| Chemical Name: | (3R)-1-[2-(1,3-benzodioxol-5-yl)ethyl]-3-(diphenylmethoxy)-piperidine, (2E)-2-butenedioate |
| Synonyms: | 扎非那星富马酸盐; UK-76654 fumarate |
| 分子量: | 531.60 |
| 分子式: | C₃₁H₃₃NO₇ |
| SMILES: | OC(/C=C/C(O)=O)=O.N1(C[C@@H](CCC1)OC(C2=CC=CC=C2)C3=CC=CC=C3)CCC4=CC5=C(C=C4)OCO5 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Zamifenacin fumarate (UK-76654 fumarate) 是一种有效的肠道选择性毒蕈碱M3受体拮抗剂。Zamifenacin 可显着降低肠易激综合症的结肠蠕动。 |
| IC50和靶点: | |
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Moriya, H., Takagi, Y., Nakanishi, T., et al.Affinity profiles of various muscarinic antagonists for cloned human muscarinic acetylcholine receptor (mAChR) subtypes and mAChRs in rat heart and submandibular glandLife Sci.64(25),2351-2358(1999)
Wallis, R.M.Pre-clinical and clinical pharmacology of selective muscarinic M3 receptor antagonistsLife Sci.56(11-12),861-868(1995)
