VU 0365114
Cat. No.:YN320333
CAS No. :1208222-39-2
产品名称: | VU 0365114 |
CAS No.: | 1208222-39-2 |
Chemical Name: | 1-([1,1′-biphenyl]-4-ylmethyl)-5-(trifluoromethoxy)-1H-indole-2,3-dione |
Synonyms: | VU 0365114;VU-0365114;VU0365114 |
分子量: | 397.35 |
分子式: | C₂₂H₁₄F₃NO₃ |
SMILES: | O=C1N(C2=CC=C(OC(F)(F)F)C=C2C1=O)CC3=CC=C(C4=CC=CC=C4)C=C3 |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | VU 0365114 是mAChR M5的正变构调节剂,其EC50值为2.7 μM。 |
IC50和靶点: | |
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In Vivo: | |
Clinical Trial: | |
Solvent & Solubility: |
Bridges, T.M., Kennedy, J.P., Hopkins, C.R., et al.Heterobiaryl and heterobiaryl ether derived M5 positive allosteric modulatorsBioorg. Med. Chem. Lett.20(19),5617-5622(2010)