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Atropine methyl bromide

Cat. No.:YN320447

  • CAS No. :2870-71-5

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    • 参考文献
    • 产品名称: Atropine methyl bromide
      CAS No.: 2870-71-5
      Chemical Name: 3-(3-hydroxy-1-oxo-2-phenylpropoxy)-8,8-dimethyl-8-azoniabicyclo[3.2.1]octane, monobromide
      Synonyms:甲溴阿托品; Methylatropine bromide
      分子量:384.31
      分子式:C₁₈H₂₆BrNO₃
      SMILES:C[N+]1([C@H]2C[C@H](OC(C(C3=CC=CC=C3)CO)=O)C[C@@H]1CC2)C.[Br-]
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
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      Purity: 98%
    • 产品描述: Atropine methyl bromide, 是毒蕈碱型受体 (mAChR)的拮抗剂,是阿托品的季铵盐,是眼科检查时用于瞳孔扩张的药物。由于其高度极性,被用于缓解婴儿幽门痉挛。它比阿托品更不易进入中枢神经系统。
      IC50和靶点:
      In Vitro:
      In Vivo:
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    • Schmeller, T., Sporer, F., Sauerwein, M., et al.Binding of tropane alkaloids to nicotinic and muscarinic acetylcholine receptorsPharmazie50(7),493-495(1995)

      Brezenoff, H.E., Xiao, Y.-F., and Vargas, H.A comparison of the central and peripheral antimuscarinic effects of atropine and methylatropine injected systemically and into the cerebral ventriclesLife Sci.42(8),905-911(1988)

      Albanus, L.Central and peripheral effects of anticholinergic compoundsActa Pharmacol. Toxicol. (Copenh)28(4),305-326(1970)

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