Biperiden Hydrochloride
Cat. No.：YN320703
| 产品名称: | Biperiden Hydrochloride |
| CAS No.: | 1235-82-1 |
| Chemical Name: | α-bicyclo[2.2.1]hept-5-en-2-yl-α-phenyl-1-piperidinepropanol, monohydrochloride |
| Synonyms: | 盐酸比哌立登; KL 373 (Hydrochloride) |
| 分子量: | 347.92 |
| 分子式: | C₂₁H₃₀ClNO |
| SMILES: | OC(C1CC2C=CC1C2)(CCN3CCCCC3)C4=CC=CC=C4.[H]Cl |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Biperiden Hydrochloride (KL 373 Hydrochloride) 是M1胆碱受体阻断剂，可作用于帕金森症。 |
| IC50和靶点: | |
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Bolden, C., Cusack, B., and Richelson, E.Antagonism by antimuscarinic and neuroleptic compounds at the five cloned human muscarinic cholinergic receptors expressed in Chinese hamster ovary cellsJ. Pharmacol. Exp. Ther.260(2),576-580(1992)
Jackisch, R., Huang, H.Y., Reimann, W., et al.Effects of the antiparkinsonian drug budipine on neurotransmitter release in central nervous system tissue in vitroJ. Pharmacol. Exp. Ther.264(2),889-898(1993)
Jackisch, R., Kruchen, A., Sauermann, W., et al.The antiparkinsonian drugs budipine and biperiden are use-dependent (uncompetitive) NMDA receptor antagonistsEur. J. Pharmacol.264(2),207-211(1994)
Gothóni, P., Lehtinen, M., and Fincke, M.Drugs for Parkinson's disease reduce tremor induced by physostigmineNaunyn Schmiedebergs Arch. Pharmacol.323(3),205-210(1983)
