VU0152100
Cat. No.：YN320727
| 产品名称: | VU0152100 |
| CAS No.: | 409351-28-6 |
| Chemical Name: | 3-amino-N-[(4-methoxyphenyl)methyl]-4,6-dimethyl-thieno[2,3-b]pyridine-2-carboxamide |
| Synonyms: | VU152100 |
| 分子量: | 341.43 |
| 分子式: | C₁₈H₁₉N₃O₂S |
| SMILES: | CC1=C2C(SC(C(NCC3=CC=C(OC)C=C3)=O)=C2N)=NC(C)=C1 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | VU0152100是M4 mAChR的变构增强剂，EC50为380 nM。 |
| IC50和靶点: | |
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| Solvent & Solubility: |
Brady, A.E., Jones, C.K., Bridges, T.M., et al.Centrally active allosteric potentiators of the M4 muscarinic acetylcholine receptor reverse amphetamine-induced hyperlocomotor activity in ratsJ. Pharmacol. Exp. Ther.327(3),941-953(2008)
Dencker, D., Weikop, P., Sørensen, G., et al.An allosteric enhancer of M4 muscarinic acetylcholine receptor function inhibits behavioral and neurochemical effects of cocainePsychopharmacology224(2),277-287(2012)
