Xanomeline oxalate
Cat. No.：YN320734
| 产品名称: | Xanomeline oxalate |
| CAS No.: | 141064-23-5 |
| Chemical Name: | 3-[4-(hexyloxy)-1,2,5-thiadiazol-3-yl]-1,2,5,6-tetrahydro-1-methyl-pyridine, ethanedioate |
| Synonyms: | LY246708 oxalate |
| 分子量: | 371.45 |
| 分子式: | C₁₆H₂₅N₃O₅S |
| SMILES: | CN1CCC=C(C2=NSN=C2OCCCCCC)C1.O=C(O)C(O)=O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Xanomeline oxalate (LY246708 oxalate) 是一种有效的、选择性毒蕈碱受体激动剂 (SMRA)，可刺激体内的磷酸肌醇水解。 Xanomeline oxalate 可用于研究阿尔茨海默氏病。 |
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Heinrich, J.N., Butera, J.A., Carrick, T., et al.Pharmacological comparison of muscarinic ligands: Historical versus more recent muscarinic M1-preferring receptor agonistsEur. J. Pharmacol.605(1-3),53-56(2009)
Stanhope, K.J., Mirza, N.R., Dickerdike, M.J., et al.The muscarinic receptor agonist xanomeline has an antipsychotic-like profile in the ratJ. Pharmacol. Exp. Ther.299(2),782-792()
Andersen, M.B., Fink-Jensen, A., Peacock, L., et al.The muscarinic M1/M4 receptor agonist xanomeline exhibits antipsychotic-like activity in Cebus apella monkeysNeuropsychopharmacology28(6),1168-1175(2003)
Messer, W.S., Jr.The utility of muscarinic agonists in the treatment of Alzheimer's diseaseJ. Mol. Neurosci.19(1-2),187-193(2002)
