Aclidinium Bromide
Cat. No.：YN320822
CAS No. ：320345-99-1
| 产品名称: | Aclidinium Bromide |
| CAS No.: | 320345-99-1 |
| Chemical Name: | (3R)-3-[(2-hydroxy-2,2-di-2-thienylacetyl)oxy]-1-(3-phenoxypropyl)-1-azoniabicyclo[2.2.2]octane, monobromide |
| Synonyms: | 阿地溴铵; LAS 34273; LAS-W 330 |
| 分子量: | 564.55 |
| 分子式: | C₂₆H₃₀BrNO₄S₂ |
| SMILES: | O=C(O[C@H]1C[N+]2(CCCOC3=CC=CC=C3)CCC1CC2)C(C4=CC=CS4)(O)C5=CC=CS5.[Br-] |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Aclidinium Bromide (LAS 34273) 是长效的可吸入型毒蕈碱 (muscarinic) 拮抗剂，有潜力用于慢性阻塞性肺病 (COPD) 的研究。 |
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Gavaldà, A., Miralpeix, M.R., I. , Otal, R., et al.Characterization of aclidinium bromide, a novel inhaled muscarinic antagonist, with long duration of action and a favorable pharmacological profileJ. Pharmacol. Exp. Ther.331(2),740-751(2009)
Rogliani, P., Calzetta, L., Ora, J., et al.Pharmacological assessment of the onset of action of aclidinium and glycopyrronium versus tiotropium in COPD patients and human isolated bronchiEur. J. Pharmacol.761,383-390(2015)
