TBPB
Cat. No.：YN320892
CAS No. ：634616-95-8
| 产品名称: | TBPB |
| CAS No.: | 634616-95-8 |
| Chemical Name: | 1,3-dihydro-1-[1'-[(2-methylphenyl)methyl][1,4'-bipiperidin]-4-yl]-2H-benzimidazol-2-one |
| Synonyms: | |
| 分子量: | 404.55 |
| 分子式: | C₂₅H₃₂N₄O |
| SMILES: | O=C1N(C2CCN(C3CCN(CC4=C(C)C=CC=C4)CC3)CC2)C5=CC=CC=C5N1 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | TBPB是M1 mAChR变构激动剂，EC50值为289nM，调节amyloid的加工和小鼠体内具有抗精神病药物等活性。 |
| IC50和靶点: | |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
Jones, C.K., Brady, A.E., Davis, A.A., et al.Novel selective allosteric activator of the M1 muscarinic acetylcholine receptor regulates amyloid processing and produces antipsychotic-like activity in ratsJ. Neurosci.28(41),10422-10433(2008)
