Pirenzepine dihydrochloride
Cat. No.：YN321107
| 产品名称: | Pirenzepine dihydrochloride |
| CAS No.: | 29868-97-1 |
| Chemical Name: | 5,11-dihydro-11-[2-(4-methyl-1-piperazinyl)acetyl]-6H-pyrido[2,3-b][1,4]benzodiazepin-6-one, dihydrochloride |
| Synonyms: | LS519 |
| 分子量: | 424.32 |
| 分子式: | C₁₉H₂₃Cl₂N₅O₂ |
| SMILES: | O=C1NC2=CC=CN=C2N(C(CN3CCN(C)CC3)=O)C4=CC=CC=C14.[H]Cl.[H]Cl |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Pirenzepine dihydrochloride (LS519) 是一种选择性M1型毒蕈碱受体拮抗剂。 |
| IC50和靶点: | |
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Doods, H.N., Entzeroth, M., Ziegler, H., et al.Pharmacological profile of selective muscarinic receptor antagonists on guinea-pig ileal smooth muscleEur. J. Pharmacol.253(3),275-281(1994)
Del Soldato, P., and Pagani, F.Pharmacodynamic evaluation of selective antimuscarinic properties of pirenzepine in the ratPharmacol. Res. Commun.14(3),279-287(1982)
Luft, W.A., Ming, Y., and Stell, W.K.Variable effects of previously untested muscarinic receptor antagonists on experimental myopiaInvest. Ophthalmol. Vis. Sci.44(3),1330-1338(2003)
