Glycopyrrolate
Cat. No.:YN321145
CAS No. :596-51-0
产品名称: | Glycopyrrolate |
CAS No.: | 596-51-0 |
Chemical Name: | 3-[(2-cyclopentyl-2-hydroxy-2-phenylacetyl)oxy]-1,1-dimethyl-pyrrolidinium, monobromide |
Synonyms: | 格隆溴铵; Glycopyrronium bromide; |
分子量: | 398.33 |
分子式: | C₁₉H₂₈BrNO₃ |
SMILES: | C[N+]1(C)CC(OC(C(O)(C2CCCC2)C3=CC=CC=C3)=O)CC1.[Br-] |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | Glycopyrrolate (Glycopyrronium bromide) 是竞争性毒蕈碱拮抗剂,可解痉挛。 |
IC50和靶点: | |
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Gavaldà, A., Ramos, I., Carcasona, C., et al.The in vitro and in vivo profile of aclidinium bromide in comparison with glycopyrronium bromidePulm. Pharmacol. Ther.28(2),114-1121(2014)
Rogliani, P., Calzetta, L., Ora, J., et al.Pharmacological assessment of the onset of action of aclidinium and glycopyrronium versus tiotropium in COPD patients and human isolated bronchiEur. J. Pharmacol.761,383-390(2015)
Burger, D.M., Wiestner, T., Hubler, M., et al.Effect of anticholinergics (atropine, glycopyrrolate) and prokinetics (metoclopramide, cisapride) on gastric motility in beagles and labrador retrieversJ. Vet. Med. A Physiol. Pathol. Clin. Med.53(2),97-107(2006)