Tolterodine tartrate
Cat. No.:YN321317
CAS No. :124937-52-6
产品名称: | Tolterodine tartrate |
CAS No.: | 124937-52-6 |
Chemical Name: | 2-[(1R)-3-[bis(1-methylethyl)amino]-1-phenylpropyl]-4-methyl-phenol, 2R,3R-dihydroxybutanedioate |
Synonyms: | Kabi-2234; PNU-200583E |
分子量: | 475.57 |
分子式: | C₂₆H₃₇NO₇ |
SMILES: | OC1=CC=C(C=C1[C@H](CCN(C(C)C)C(C)C)C2=CC=CC=C2)C.O=C([C@@H]([C@H](C(O)=O)O)O)O |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | Tolterodine Tartrate (Kabi-2234; PNU-200583E) 是一种有效的毒蕈碱受体拮抗剂,体内对膀胱具有选择性。 |
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Jones, L.H., Randall, A., Napier, C., et al.Design and synthesis of a fluorescent muscarinic antagonistBioorg. Med. Chem. Lett.18(2),825-827(2008)
Kobayashi, S., Ikeda, K., and Miyata, K.Comparison of in vitro selectivity profiles of solifenacin succinate (YM905) and current antimuscarinic drugs in bladder and salivary glands: A Ca2+ mobilization study in monkey cellsLife Sci.74(7),843-853(2004)
McNamara, A., Pulido-Rios, M.T., Sweazey, S., et al.Pharmacological properties of TD-6301, a novel bladder selective muscarinic receptor antagonistEur. J. Pharmacol.605(1-3),145-152(2009)