Solifenacin Succinate
Cat. No.：YN321318
CAS No. ：242478-38-2
| 产品名称: | Solifenacin Succinate |
| CAS No.: | 242478-38-2 |
| Chemical Name: | (1S)-(3R)-1-azabicyclo[2.2.2]oct-3-yl 3,4-dihydro-1-phenyl-2(1H)-isoquinolinecarboxylate, butanedioic acid |
| Synonyms: | 索非那新琥珀酸盐; YM905 |
| 分子量: | 480.55 |
| 分子式: | C₂₇H₃₂N₂O₆ |
| SMILES: | O=C(O[C@H]1CN2CCC1CC2)N3[C@H](C4=C(CC3)C=CC=C4)C5=CC=CC=C5.O=C(CCC(O)=O)O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Solifenacin Succinate (YM905) 是毒蕈碱受体 (muscarinic receptor) 拮抗剂，对M1，M2和M3受体的pKi值分别为 7.6、6.9 和 8.0。 |
| IC50和靶点: | |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
Hegde, S.S.Muscarinic receptors in the bladder: From basic research to therapeuticsBr. J. Pharmacol.147(2),S80-S87(2006)
Ikeda, K., Koboyashi, S., Suzuki, M., et al.M3 receptor antagonism by the novel antimuscarinic agent solifenacin in the urinary bladder and salivary glandNaunyn Schmiedebergs Arch. Pharmacol.366(2),97-103(2002)
