Fesoterodine fumarate
Cat. No.：YN321335
CAS No. ：286930-03-8
| 产品名称: | Fesoterodine fumarate |
| CAS No.: | 286930-03-8 |
| Chemical Name: | 2-methyl-propanoic acid, 2-[(1R)-3-[bis(1-methylethyl)amino]-1-phenylpropyl]-4-(hydroxymethyl)phenyl ester, (2E)-2-butenedioate |
| Synonyms: | 富马酸非索罗定 |
| 分子量: | 527.65 |
| 分子式: | C₃₀H₄₁NO₇ |
| SMILES: | OCC1=CC([C@H](CCN(C(C)C)C(C)C)C2=CC=CC=C2)=C(C=C1)OC(C(C)C)=O.OC(/C=C/C(O)=O)=O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Fesoterodine Fumarate 是一种口服有效，非亚型选择性的，竞争性毒蕈碱受体 (mAChR) 拮抗剂，对 M1，M2，M3，M4，M5 受体的pKi值分别为 8.0，7.7，7.4，7.3，7.5。Fesoterodine Fumarate 用于膀胱过度活动症 (OAB)。 |
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Ney, P., Pandita, R.K., Newgreen, D.T., et al.Pharmacological characterization of a novel investigational antimuscarinic drug, fesoterodine, in vitro and in vivoBJU Int.101(8),1036-1042(2008)
Biardeau, X., Przydacz, M., Aharony, S., et al.Early fesoterodine fumarate administration prevents neurogenic detrusor overactivity in a spinal cord transected rat modelPLoS One12(1),e0169694(2017)
