Methacholine chloride
Cat. No.：YN321348
| 产品名称: | Methacholine chloride |
| CAS No.: | 62-51-1 |
| Chemical Name: | 2-(acetyloxy)-N,N,N-trimethyl-1-propanaminium, monochloride |
| Synonyms: | 醋甲胆碱; Acetyl-β-methylcholine chloride |
| 分子量: | 195.69 |
| 分子式: | C₈H₁₈ClNO₂ |
| SMILES: | CC(OC(C)=O)C[N+](C)(C)C.[Cl-] |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Methacholine (Acetyl-β-methylcholine) chloride 在副交感神经系统中起毒蕈碱-3 受体 (muscarinic M3 receptor) 激动剂的作用。Methacholine chloride 直接作用于平滑肌上的乙酰胆碱受体，引起收缩和气道狭窄。Methacholine challenges 被广泛用于测量气道高反应性 (AHR)，作为评估哮喘样症状和正常静息呼气流速的诊断辅助手段。 |
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Fisher, J.T., Vincent, S.G., Gomeza, J., et al.Loss of vagally mediated bradycardia and bronchoconstriction in mice lacking M2 or M3 muscarinic acetylcholine receptorsFASEB J.18(67),711-713(2004)
Choi, S.H., Sheen, Y.H., Kim, M.A., et al.Clinical implications of oscillatory lung function during methacholine bronchoprovocation testing of preschool childrenBiomed. Res. Int.2017,1-9(2017)
