Pilocarpine Hydrochloride
Cat. No.：YN321565
| 产品名称: | Pilocarpine Hydrochloride |
| CAS No.: | 54-71-7 |
| Chemical Name: | (3S,4R)-3-ethyldihydro-4-[(1-methyl-1H-imidazol-5-yl)methyl]-2(3H)-furanone, monohydrochloride |
| Synonyms: | 盐酸毛果芸香碱 |
| 分子量: | 244.72 |
| 分子式: | C₁₁H₁₇ClN₂O₂ |
| SMILES: | CN1C(C[C@@H](COC2=O)[C@@H]2CC)=CN=C1.Cl |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Pilocarpine Hydrochloride 是一种选择性的 M3 型毒蕈碱乙酰胆碱受体 (M3 muscarinic receptor) 激动剂。 |
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Vanderheyden, P., Gies, J.-P., Ebinger, G., et al.Human M1-, M2- and M3-muscarinic cholinergic receptors: Binding characteristics of agonists and antagonistsJ. Neurol. Sci.97(1),67-80(1990)
Renzi, A., Colombari, E., Mattos Filho, T.R., et al.Involvement of the central nervous system in the salivary secretion induced by pilocarpine in ratsJ. Dent. Res.72(11),1481-1484(1993)
Lorenzetti, O.J.The influence of epinephrine and pilocarpine upon intraocular pressure following single and combination installationOphthal. Res.2(6),328-336(1971)
Kokate, T.G., Cohen, A.L., Karp, E., et al.Neuroactive steroids protect against pilocarpine- and kainic acid-induced limbic seizures and status epilepticus in miceNeuropharmacology35(8),1049-1056(1996)
Ma, L., Wang, L., Yang, F., et al.Disease-modifying effects of RHC80267 and JZL184 in a pilocarpine mouse model of temporal lobe epilepsyCNS Neurosci. Ther.20(10),905-915(2014)
Smolders, I., Khan, G.M., Manil, H., et al.NMDA receptor-mediated pilocarpine-induced seizures: Characterization in freely moving rats by microdialysisBr. J. Pharmacol.121(6),1171-1179(1997)
