Trihexyphenidyl hydrochloride
Cat. No.：YN321638
| 产品名称: | Trihexyphenidyl hydrochloride |
| CAS No.: | 52-49-3 |
| Chemical Name: | α-cyclohexyl-α-phenyl-1-piperidinepropanol, monohydrochloride |
| Synonyms: | 盐酸苯海索 |
| 分子量: | 337.93 |
| 分子式: | C₂₀H₃₂ClNO |
| SMILES: | OC(C1=CC=CC=C1)(C2CCCCC2)CCN3CCCCC3.[H]Cl |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Trihexyphenidyl盐酸盐是抗毒蕈碱类的抗帕金森剂, 结合至M1毒蕈碱受体。 |
| IC50和靶点: | |
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Giachetti, A., Giraldo, E., Ladinsky, H., et al.Binding and functional profiles of the selective M1 muscarinic receptor antagonists trihexyphenidyl and dicyclomineBr. J. Pharmacol.89(1),83-90(1986)
Fjalland, B., Christensen, A.V., and Hyttel, J.Peripheral and central muscarinic receptor affinity of psychotropic drugsNaunyn. Schmiedebergs. Arch. Pharmacol.301(1),5-9(1977)
Rose, S.J., Yu, X.Y., Heinzer, A.K., et al.A new knock-in mouse model of ʟ-DOPA-responsive dystoniaBrain138(Pt 10),2987-3002(2015)
