Dicyclomine hydrochloride
Cat. No.：YN321646
| 产品名称: | Dicyclomine hydrochloride |
| CAS No.: | 67-92-5 |
| Chemical Name: | [1,1'-bicyclohexyl]-1-carboxylic acid, 2-(diethylamino)ethyl ester, monohydrochloride |
| Synonyms: | Dicycloverine hydrochloride |
| 分子量: | 345.95 |
| 分子式: | C₁₉H₃₆ClNO₂ |
| SMILES: | O=C(C1(C2CCCCC2)CCCCC1)OCCN(CC)CC.[H]Cl |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Dicyclomine hydrochloride 是一种有效的口服活性毒蕈碱胆碱能受体 (muscarinic cholinergic receptors) 拮抗剂。Dicyclomine hydrochloride 对 M1 受体亚型 (Ki=5.1 nM) 和 M2 受体亚型 (Ki=54.6 nM) 在刷缘膜和基底质膜中均表现出较高的亲和力。Dicyclomine hydrochloride是一种抗痉挛试剂，在体内可缓解胃肠道平滑肌痉挛。 |
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Kunysz, E.L., Michel, A.D., and Whiting, R.L.Functional and direct binding studies using subtype selective muscarinic receptor antagonistsBr. J. Pharmacol.93(3),491-500(1988)
Subissi, A., Brunori, P., and Bachi, M.Effects of spasmolytics on K+-induced contraction of rat intestine in vivoEur. J. Pharmacol.96(3-4),295-301(1983)
