FITM
Cat. No.：YN320203
CAS No. ：932737-65-0
| 产品名称: | FITM |
| CAS No.: | 932737-65-0 |
| Chemical Name: | 4-fluoro-N-methyl-N-[4-[6-[(1-methylethyl)amino]-4-pyrimidinyl]-2-thiazolyl]-benzamide |
| Synonyms: | 4-氟-N-[4-[6-(异丙基氨基)嘧啶-4-基]-1,3-噻唑-2-基]-N-甲基苯甲酰胺 |
| 分子量: | 371.43 |
| 分子式: | C₁₈H₁₈FN₅OS |
| SMILES: | O=C(N(C)C1=NC(C2=NC=NC(NC(C)C)=C2)=CS1)C3=CC=C(F)C=C3 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | FITM是mGlu1受体的负变构调节剂，Ki值为2.5 nM。 |
| IC50和靶点: | [{name:"mGlu1:2.5 nM (Ki)"}] |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
Satoh, A., Nagatomi, Y., Hirata, Y., et al.Discovery and in vitro and in vivo profiles of 4-fluoro-N-[4-[6-(isopropylamino)pyrimidin-4-yl]-1,3-thiazol-2-yl]-N-methylbenzamide as novel class of an orally active metabotropic glutamate receptor 1 (mGluR1) antagonistBioorg. Med. Chem. Lett.19(18),5464-5468(2009)
