YM-298198 hydrochloride
Cat. No.：YN320268
CAS No. ：1216398-09-2
| 产品名称: | YM-298198 hydrochloride |
| CAS No.: | 1216398-09-2 |
| Chemical Name: | 6-amino-N-cyclohexyl-N,3-dimethyl-thiazolo[3,2-a]benzimidazole-2-carboxamide, monohydrochloride |
| Synonyms: | YM 298198 hydrochloride |
| 分子量: | 378.92 |
| 分子式: | C₁₈H₂₃ClN₄OS |
| SMILES: | O=C(C1=C(C)N2C3=CC(N)=CC=C3N=C2S1)N(C4CCCCC4)C.[H]Cl |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | YM-298198 hydrochloride 是高亲和力、选择性、非竞争性的mGluR1的拮抗剂。YM-298198 hydrochloride 可用于神经系统疾病的研究。 |
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Kohara, A., Toya, T., Tamura, S., et al.Radioligand binding properties and pharmacological characterization of 6-amino-N-cyclohexyl-N,3-dimethylthiazolo[3,2-a]benzimidazole-2-carboxamide (YM-298198), a high-affinity, selective, and noncompetitive antagonist of metabotropic glutamate receptor type 1J. Pharmacol. Exp. Ther.315(1),163-169(2005)
Schmidt, H.D., Kimmey, B.A., Arreola, A.C., et al.Group I metabotropic glutamate receptor-mediated activation of PKC gamma in the nucleus accumbens core promotes the reinstatement of cocaine seekingAddict. Biol.20(2),285-296(2015)
