JNJ-46281222
Cat. No.：YN320534
CAS No. ：1254980-38-5
| 产品名称: | JNJ-46281222 |
| CAS No.: | 1254980-38-5 |
| Chemical Name: | |
| Synonyms: | |
| 分子量: | 414.47 |
| 分子式: | C₂₃H₂₅F₃N₄ |
| SMILES: | FC(C1=C(CN2CCC(C3=CC=CC=C3)CC2)C=CN4C1=NN=C4CC5CC5)(F)F |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | JNJ-46281222 是选择性代谢型谷氨酸 2 (mGlu2) 高效 PAM (正构变构调节剂)，具有纳摩尔摩尔亲和力(Kd=1.7 nM) 和高调节效能 (pEC50= 7.71) 的高效 PAM (正构变构调节剂)。 |
| IC50和靶点: | [{name:"mGluR2:1.7 nM (Kd)"}] |
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| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
