VU0361737
Cat. No.：YN320865
CAS No. ：1161205-04-4
| 产品名称: | VU0361737 |
| CAS No.: | 1161205-04-4 |
| Chemical Name: | N-(4-chloro-3-methoxyphenyl)-2-pyridinecarboxamide |
| Synonyms: | ML-128 |
| 分子量: | 262.69 |
| 分子式: | C₁₃H₁₁ClN₂O₂ |
| SMILES: | ClC(C=C1)=C(OC)C=C1NC(C2=NC=CC=C2)=O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | VU0361737 (ML-128) 是一种高效、选择性的，中枢神经系统 (CNS) 渗透性的代谢型谷氨酸受体 4 正变构调节剂 (mGluR4 PAM) ,对人类和大鼠 mGluR4 作用的EC50值分别为 240 nM 和 110 nM。VU0361737 具有神经保护作用，有潜力用于帕金森氏病的研究 |
| IC50和靶点: | [{name:"Human mGlu4:240 nM (EC50)"},{name: "Rat mGlu4:110 nM (EC50)"}] |
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