Varenicline Tartrate
Cat. No.：YN360013
CAS No. ：375815-87-5
| 产品名称: | Varenicline Tartrate |
| CAS No.: | 375815-87-5 |
| Chemical Name: | 7,8,9,10-tetrahydro-6,10-methano-6H-pyrazino[2,3-h][3]benzazepine-(2R,3R)-dihydroxybutanedioate |
| Synonyms: | 酒石酸伐尼克兰; CP 526555-18 |
| 分子量: | 361.35 |
| 分子式: | C₁₇H₁₉N₃O₆ |
| SMILES: | O=C(O)[C@H](O)[C@@H](O)C(O)=O.C1(C2CC3CNC2)=C3C=C(N=CC=N4)C4=C1 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Varenicline Tartrate (CP 526555-18) 是α4β2 nAChR烟碱乙酰胆碱受体的部分激动剂 (EC50=2.3 μM)。Varenicline Tartrate 是 α3β4 nAChR 和 α7 nAChR 乙酰胆碱受体完全激动剂，EC50值分别为 55 μM 和 18 μM。Varenicline 是一种基于胞嘧啶结构的烟碱配体，有潜力用于戒烟方面的研究。 |
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Mihalak, K.B., Carroll, F.I., and Luetje, C.W.Varenicline is a partial agonist at α4β2 and a full agonist at α7 neuronal nicotinic receptorsMol. Pharm.70(3),801-805(2006)
