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Hexamethonium Bromide

Cat. No.:YN360807

  • CAS No. :55-97-0

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    • 参考文献
    • 产品名称: Hexamethonium Bromide
      CAS No.: 55-97-0
      Chemical Name: N1,N1,N1,N6,N6,N6-hexamethyl-1,6-hexanediaminium, dibromide
      Synonyms:Hexamethonium Dibromide,Simpatoblock,Gangliostat,溴化六甲铵,六甲溴铵
      分子量:362.19
      分子式:C₁₂H₃₀Br₂N₂
      SMILES:C[N+](C)(C)CCCCCC[N+](C)(C)C.[Br-].[Br-]
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
      Select Batch:
      Purity: 98%
    • 产品描述: Hexamethonium Bromide 是非去极化的神经节阻断剂,是 nAChR 拮抗剂。
      IC50和靶点:
      In Vitro:
      In Vivo:
      Clinical Trial:
      Solvent & Solubility:
    • Gosling, J.A., and Lu, T.C.Uptake and distribution of some quaternary ammonium compounds in the central nervous system of the ratJ. Pharmacol. Exp. Ther.167(1),56-62(1969)

      Papke, R.L., Wecker, L., and Stitzel, J.A.Activation and inhibition of mouse muscle and neuronal nicotinic acetylcholine receptors expressed in Xenopus oocytesJ. Pharmacol. Exp. Ther.333(2),501-518(2010)

      McKinstry, D.N., and Koelle, G.B.Effects of drugs on acetylcholine release from the cat superior cervical ganglion by carbachol and by preganglionic stimulationJ. Pharmacol. Exp. Ther.157(2),328-336(1967)

      Nishida, Y., Tandai-Hiruma, M., Kemuriyama, T., et al.Long-term blood pressure control: is there a set-point in the brain?J. Physiol. Sci.62(3),147-161(2012)

      Malin, D.H., Lake, J.R., Schopen, C.K., et al.Nicotine abstinence syndrome precipitated by central but not peripheral hexamethoniumPharmacol. Biochem. Behav.58(3),695-699(1997)

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