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Decamethonium Bromide

Cat. No.:YN360808

  • CAS No. :541-22-0

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    • 产品名称: Decamethonium Bromide
      CAS No.: 541-22-0
      Chemical Name: N1,N1,N1,N10,N10,N10-hexamethyl-1,10-decanediaminium, dibromide
      Synonyms:十烃溴铵
      分子量:418.29
      分子式:C₁₆H₃₈Br₂N₂
      SMILES:C[N+](C)(C)CCCCCCCCCC[N+](C)(C)C.[Br-].[Br-]
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
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      Purity: 98%
    • 产品描述: 溴化Decamethonium是烟碱型乙酰胆碱受体(nAChR)部分激动剂和神经肌肉阻断剂。
      IC50和靶点:
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    • Paton, W.D., and Zaimis, E.J.The action of D-tubocurarine and of decamethonium on respiratory and other muscles in the catJ. Physiol.112(3-4),311-331(1951)

      Papke, R.L., Wecker, L., and Stitzel, J.A.Activation and inhibition of mouse muscle and neuronal nicotinic acetylcholine receptors expressed in Xenopus oocytesJ. Pharmacol. Exp. Ther.333(2),501-518(2010)

      Eaton, J.B., Peng, J.-H., Schroeder, K.M., et al.Characterization of human α4β2-nicotinic acetylcholine receptors stably and heterologously expressed in native nicotinic receptor-null SH-EP1 human epithelial cellsMol. Pharmacol.64(6),1283-1294(2003)

      Robaire, B., and Kato, G.Effects of edrophonium, serine, decamethonium, d-tubocurarine, and gallamine on the kinetics of membrane-bound and solubilized eel acetylcholinesteraseMol. Pharmacol.11(6),722-734(1974)

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