Lobeline hydrochloride
Cat. No.：YN360846
CAS No. ：134-63-4
| 产品名称: | Lobeline hydrochloride |
| CAS No.: | 134-63-4 |
| Chemical Name: | 2-[(2R,6S)-6-[(2S)-2-hydroxy-2-phenylethyl]-1-methyl-2-piperidinyl]-1-phenyl-ethanone, monohydrochloride |
| Synonyms: | 盐酸洛贝林; α |
| 分子量: | 373.92 |
| 分子式: | C₂₂H₂₈ClNO₂ |
| SMILES: | CN1[C@@H](CC(C2=CC=CC=C2)=O)CCC[C@H]1C[C@H](O)C3=CC=CC=C3.[H]Cl |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Lobeline hydrochloride 是烟碱样受体激动剂, 作为有效的神经元烟碱受体α3β2和α4β2拮抗剂。 |
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Flammia, D., Dukat, M., Damaj, M.I., et al.Lobeline: Structure-affinity investigation of nicotinic acetylcholinergic receptor bindingJ. Med. Chem.42(18),3726-3731(1999)
Levin, E.D., and Christopher, C.N.Lobeline-induced learning improvement of rats in the radial-arm mazePharmacol. Biochem. Behav.76(1),133-139(2003)
Roni, M.A., and Rahman, S.Antidepressant-like effects of lobeline in mice: Behavioral, neurochemical, and neuroendocrine evidenceProg. Neuropsychopharmacol. Biol. Psychiatry41,44-51(2013)
