(+)-Sparteine
Cat. No.:YN361085
产品名称: | (+)-Sparteine |
CAS No.: | 492-08-0 |
Chemical Name: | (7R,7aR,14R,14aS)-dodecahydro-7,14-methano-2H,6H-dipyrido[1,2-a:1′,2′-e][1,5]diazocine |
Synonyms: | (+)-鹰爪豆碱 |
分子量: | 234.38 |
分子式: | C₁₅H₂₆N₂ |
SMILES: | [H][C@]12CCCCN1C[C@H]3C[C@@H]2CN4CCCC[C@@]34[H] |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | (+)-Sparteine 是一种天然生物碱,作为一种神经节阻滞剂。在神经细胞中,(+)-Sparteine 竞争性地抑制烟碱型乙酰胆碱受体 (nACh receptor) 活性。 |
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van Wyk, B.-E., and Verdoorn, G.H.Optical rotation of quinolizidine alkaloids: An important variable in chemosystematic studies of FabaceaePl. Syst. Evol.198(3/4),267-274(1995)
McSweeney, C.M., Foley, V.M., and McGlacken, G.P.The asymmetric alkylation of dimethylhydrazones; intermolecular chirality transfer using sparteine as chiral ligandChem. Commun. (Camb.)50(94),14817-14819(2014)
Lin, W., Zhang, K.-F., and Baudoin, O.Regiodivergent enantioselective C-H functionalization of Boc-1,3-oxazinanes and application to the synthesis of β2 and β3-amino acidsNat. Catal.2(10),882-888(2019)