TA-01
Cat. No.：YN350001
CAS No. ：1784751-18-3
| 产品名称: | TA-01 |
| CAS No.: | 1784751-18-3 |
| Chemical Name: | 4-[2-(2,6-difluorophenyl)-4-(4-fluorophenyl)-1H-imidazol-5-yl]-pyridine |
| Synonyms: | TA-01,TA01，TA 01 |
| 分子量: | 351.32 |
| 分子式: | C₂₀H₁₂F₃N₃ |
| SMILES: | FC(C=C1)=CC=C1C2=C(C3=CC=NC=C3)NC(C4=C(F)C=CC=C4F)=N2 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | TA-01 是一种有效的CK1和p38 MAPK抑制剂，对 CK1ε，CK1δ 和 p38 MAPK 的IC50值分别为 6.4 nM，6.8 nM 和 6.7 nM。 |
| IC50和靶点: | [{name:"CKIδ:6.8 nM (IC50)"},{name: "p38 MAP kinase:6.7 nM (IC50)"}] |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
Laco, F., Low, J.-L., Seow, J., et al.Cardiomyocyte differentiation of pluripotent stem cells with SB203580 analogues correlates with Wnt pathway CK1 inhibition independent of p38 MAPK signalingJ. Mol. Cell. Cardiol.80,56-70(2015)
