TA-02
Cat. No.：YN350002
CAS No. ：1784751-19-4
| 产品名称: | TA-02 |
| CAS No.: | 1784751-19-4 |
| Chemical Name: | 4-[2-(2-fluorophenyl)-4-(4-fluorophenyl)-1H-imidazol-5-yl]-pyridine |
| Synonyms: | TA-02,TA02，TA 02 |
| 分子量: | 333.33 |
| 分子式: | C₂₀H₁₃F₂N₃ |
| SMILES: | FC(C=C1)=CC=C1C2=C(C3=CC=NC=C3)NC(C4=CC=CC=C4F)=N2 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | TA-02 是 SB 203580 (HY-10256) 的一个类似物，是p38 MAPK的抑制剂，其IC50值为 20 nM。TA-02 可抑制 TGFBR-2。TA-02 和 SB 203580、SB 202190 (HY-10295) 具有相似的心源活性。 |
| IC50和靶点: | |
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| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
Laco, F., Low, J.-L., Seow, J., et al.Cardiomyocyte differentiation of pluripotent stem cells with SB203580 analogues correlates with Wnt pathway CK1 inhibition independent of p38 MAPK signalingJ. Mol. Cell. Cardiol.80,56-70(2015)
