Hesperetin
Cat. No.：YN350222
| 产品名称: | Hesperetin |
| CAS No.: | 520-33-2 |
| Chemical Name: | 2,3-dihydro-5,7-dihydroxy-2-(3-hydroxy-4-methoxyphenyl)-4H-1-benzopyran-4-one |
| Synonyms: | 橙皮素 |
| 分子量: | 302.28 |
| 分子式: | C₁₆H₁₄O₆ |
| SMILES: | O=C1C[C@@H](C2=CC=C(OC)C(O)=C2)OC3=CC(O)=CC(O)=C13 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Hesperetin 是一种天然黄烷酮类物质，为有效的，广谱的人UGT抑制剂。Hesperetin 可通过激活 p38 MAPK 来诱导凋亡。 |
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Wilcox, L.J., Borradaile, N.M., de Dreu, L.E., et al.Secretion of hepatocyte apoB is inhibited by the flavonoids, naringenin and hesperetin, via reduced activity and expression of ACAT2 and MTPJ. Lipid Res.42(5),725-734(2001)
Lee, N.K., Choi, S.H., Park, S.H., et al.Antiallergic activity of hesperidin is activated by intestinal microfloraPharmacology71(4),174-180(2004)
Jo, S.H., Kim, M.E., Cho, J.H., et al.Hesperetin inhibits neuroinflammation on microglia by suppressing inflammatory cytokines and MAPK pathwaysArch. Pharm. Res.42(8),695-703(2019)
He, W., Liu, M., Li, Y., et al.Flavonoids from Citrus aurantium ameliorate TNBS-induced ulcerative colitis through protecting colonic mucus layer integrityEur. J. Pharmacol.857,172456(2019)
Muhammad, T., Ikram, M., Ullah, R., et al.Hesperetin, a citrus flavonoid, attenuates LPS-induced neuroinflammation, apoptosis and memory impairments by modulating TLR4/NF-κB signalingNutrients11(3),648(2019)
