Dehydrocorydaline chloride
Cat. No.：YN350232
| 产品名称: | Dehydrocorydaline chloride |
| CAS No.: | 10605-03-5 |
| Chemical Name: | 5,6-dihydro-2,3,9,10-tetramethoxy-13-methyl-dibenzo[a,g]quinolizinium, monochloride |
| Synonyms: | 盐酸脱氢紫堇碱; 13-Methylpalmatine chloride |
| 分子量: | 401.88 |
| 分子式: | C₂₂H₂₄ClNO₄ |
| SMILES: | CC1=C(C=CC(OC)=C2OC)C2=C[N+]3=C1C4=CC(OC)=C(OC)C=C4CC3.[Cl-] |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Dehydrocorydaline chloride (13-Methylpalmatine chloride) 是从中药延胡索Corydalis yanhusuo中分离得到的一种生物碱。Dehydrocorydaline 调节Bax，Bcl-2蛋白表达；激活caspase-7，caspase-8，并使PARP失活。Dehydrocorydaline chloride 能增强p38 MAPK活化，具有抗炎、抗癌等功效。。Dehydrocorydaline chloride 具有强大的抗疟疾作用，并具低细胞 |
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Iwasa, K., Moriyasu, M., and Nader, B.Fungicidal and herbicidal activities of berberine related alkaloidsBiosci. Biotechnol. Biochem.64(9),1998-2000(2000)
Jin, L., Zhou, S., Zhu, S., et al.Dehydrocorydaline induced antidepressant-like effect in a chronic unpredictable mild stress mouse model via inhibiting uptake-2 monoamine transportersEur. J. Pharmacol.864,172725(2019)
Yin, Z.-Y., Li, L., Chu, S.-S., et al.Antinociceptive effects of dehydrocorydaline in mouse models of inflammatory pain involve the opioid receptor and inflammatory cytokinesSci. Rep.6,27129(2016)
Huo, W., Zhang, Y., Liu, Y., et al.Dehydrocorydaline attenuates bone cancer pain by shifting microglial M1/M2 polarization toward the M2 phenotypeMol. Pain14,1744806918781733(2018)
