Rhoifolin
Cat. No.：YN350233
| 产品名称: | Rhoifolin |
| CAS No.: | 17306-46-6 |
| Chemical Name: | 7-[[2-O-(6-deoxy-α-L-mannopyranosyl)-β-D-glucopyranosyl]oxy]-5-hydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one |
| Synonyms: | 野漆树苷 |
| 分子量: | 578.52 |
| 分子式: | C₂₇H₃₀O₁₄ |
| SMILES: | O=C(C=C(C1=CC=C(O)C=C1)OC2=CC(O[C@H](O[C@H](CO)[C@@H](O)[C@@H]3O)[C@@H]3O[C@@](O[C@@H](C)[C@H](O)[C@H]4O)([H])[C@@H]4O)=C5)C2=C5O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Rhoifolin 是从琯溪蜜柚 (Citrus grandis) 叶子分离的黄酮糖苷。 Rhoifolin 通过增强脂联素分泌，胰岛素受体-β (insulin receptor-β) 的酪氨酸磷酸化和GLUT4易位有益于糖尿病并发症。 Rhoifolin 通过 RANKL 诱导的NF-κB和MAPK途径改善钛颗粒刺激的骨溶解并减弱破骨细胞生成。 |
| IC50和靶点: | |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
Xiong, L., Lu, H., Hu, Y., et al.In vitro anti-motile effects of rhoifolin, a flavonoid extracted from Callicarpa nudiflora on breast cancer cells via downregulating podocalyxin-ezrin interaction during epithelial mesenchymal transitionPhytomedicine93,153486(2021)
Jo, S., Kim, S., Shin, D.H., et al.Inhibition of SARS-CoV 3CL protease by flavonoidsJ. Enzyme Inhib. Med. Chem.35(1),145-151(2020)
Brinza, I., Abd-Alkhalek , A.M., El-Raey , M.A., et al.Ameliorative effects of rhoifolin in scopolamine-induced amnesic zebrafish (Danio rerio) modelAntioxidants (Basel)9(7),580(2020)
Fang, J., Cao, Z., Song, X., et al.Rhoifolin alleviates inflammation of acute inflammation animal models and LPS-Induced RAW264.7 cells via IKKβ/NF-κB signaling pathwayInflammation43(6),2191-2201(2020)
Yan, J., Ni, B., Sheng, G., et al.Rhoifolin ameliorates osteoarthritis via regulating autophagyFront. Pharmacol.12,661072(2021)
