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Ferulic acid methyl ester

Cat. No.:YN350275

  • CAS No. :2309-07-1

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    • 生物活性
    • 参考文献
    • 产品名称: Ferulic acid methyl ester
      CAS No.: 2309-07-1
      Chemical Name: 3-(4-hydroxy-3-methoxyphenyl)-2-propenoic acid, methyl ester
      Synonyms:Methyl ferulate
      分子量:208.21
      分子式:C₁₁H₁₂O₄
      SMILES:O=C(/C=C/C1=CC=C(C(OC)=C1)O)OC
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
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      Purity: 98%
    • 产品描述: Ferulic acid methyl ester (Methyl ferulate) 是从Stemona tuberosa中分到的阿魏酸衍生物,具有抗氧化、抗炎作用。Ferulic acid methyl ester 能够透过细胞膜和血脑屏障,清除自由基,可用于神经退行性疾病的研究。在原发性骨髓源性巨噬细胞中,Ferulic acid methyl ester 抑制 COX-2 的表达,降低p-p38和 p-JNK 的水平。
      IC50和靶点:
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    • Huang, M.T., Smart, R.C., Wong, C., et al.Inhibitory effect of curcumin, chlorogenic acid, caffeic acid, and ferulic acid on tumor promotion in mouse skin by 12-O-tetradecanoylphorbol-13-acetateCancer Res.48(21),5941-5946(1988)

      Conney, A.H., Lysz, T., Ferraro, T., et al.Inhibitory effect of curcumin and some related dietary compounds on tumor promotion and arachidonic acid metabolism in mouse skinAdv. Enzyme Regul.31,385-396(1991)

      Iwahashi, H., Nishizaki, K., and Takagi, I.Cytochrome c catalyzes the formation of pentyl radical and octanoic acid radical from linoleic acid hydroperoxideBiochem. J.361,57-66(2002)

      Sudheer, A.R., Muthukumaran, S., Devipriya, N.A., et al.Influence of ferulic acid on nicotine-induced lipid peroxidation, DNA damage and inflammation in experimental rats as compared to N-acetylcysteineToxicology243,317-329(2008)

      Sultana, R.Ferulic acid ethyl ester as a potential therapy in neurodegenerative disordersBiochim. Biophys. Acta1822(5),748-752(2012)

      Garrido, J., Gaspar, A., Garrido, E.M., et al.Alkyl esters of hydroxycinnamic acids with improved antioxidant activity and lipophilicity protect PC12 cells against oxidative stressBiochimie94(4),961-967(2012)

      Phuong, N.T.M., Cuong, T.T., and Quang, D.N.Anti-inflammatory ctivity of methyl ferulate isolated from Stemona tuberosa LourAsian Pac. J. Trop. Med.7(Suppl 1),S327-S331(2014)

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