ML240
Cat. No.：YN290467
CAS No. ：1346527-98-7
| 产品名称: | ML240 |
| CAS No.: | 1346527-98-7 |
| Chemical Name: | 2-(2-amino-1H-benzimidazol-1-yl)-8-methoxy-N-(phenylmethyl)-4-quinazolinamine |
| Synonyms: | |
| 分子量: | 396.44 |
| 分子式: | C₂₃H₂₀N₆O |
| SMILES: | COC1=CC=CC2=C(NCC3=CC=CC=C3)N=C(N4C(N)=NC5=CC=CC=C45)N=C12 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | ML240 是一种有效的p97抑制剂，抑制 p97 ATPase，IC50值为 100 nM。 |
| IC50和靶点: | |
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| Solvent & Solubility: |
Chou, T.F., Li, K., Frankowski, K.J., et al.Structure-activity relationship study reveals ML240 and ML241 as potent and selective inhibitors of p97 ATPaseChemMedChem8(2),297-312(2013)
Chou, T.F., Bulfer, S.L., Weihl, C.C., et al.Specific inhibition of p97/VCP ATPase and kinetic analysis demonstrate interaction between D1 and D2 ATPase domainsJ. Mol. Biol.426(15),2886-2899(2014)
