WAY 316606
Cat. No.：YN450029
CAS No. ：915759-45-4
规格
价格(RMB)
库存
| 产品名称: | WAY 316606 |
| CAS No.: | 915759-45-4 |
| Chemical Name: | 5-(phenylsulfonyl)-N-4-piperidinyl-2-(trifluoromethyl)-benzenesulfonamide |
| Synonyms: | WAY-316606,WAY 316606,WAY316606 |
| 分子量: | 448.48 |
| 分子式: | C₁₈H₁₉F₃N₂O₄S₂ |
| SMILES: | O=S(C1=CC(S(=O)(C2=CC=CC=C2)=O)=CC=C1C(F)(F)F)(NC3CCNCC3)=O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | WAY 316606 是一种分泌蛋白sFRP-1抑制剂，是分泌性糖蛋白Wnt的拮抗剂，在 FP 结合检测使用中，WAY-316606 作用于 sFRP-1 的IC50为 0.5 μM。 |
| IC50和靶点: | |
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| Solvent & Solubility: |
Moore, W.J., Kern, J.C., Bhat, R., et al.Modulation of Wnt signaling through inhibition of secreted frizzled-related protein I (sFRP-1) with N-substituted piperidinyl diphenylsulfonyl sulfonamides: Part IIBioorg. Med. Chem.18(1),190-201(2010)
Bodine, P.V., Stauffer, B., Ponce-de-Leon, H., et al.A small molecule inhibitor of the Wnt antagonist secreted frizzled-related protein-1 stimulates bone formationBone44(6),1063-1068(2009)
